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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Neuroprotective effects of ex vivo-expanded regulatory T cells on trimethyltin-induced neurodegeneration in mice

Fig. 7

Treg has neuroprotective effects by modulating microglial polarization in TMT-intoxicated mice. Ex vivo expanded and adoptively transferred Tregs ameliorates hippocampal neurodegeneration in TMT-intoxicated mice. Tregs promotes microglial phenotype shift from pro-inflammatory M1 to anti-inflammatory M2, resulting in a neuroprotective effects on behavioral deficits, memory formation, neuronal loss, and neuroinflammation

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Journal of Neuroinflammation

ISSN: 1742-2094