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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Sciatic nerve stimulation alleviates acute neuropathic pain via modulation of neuroinflammation and descending pain inhibition in a rodent model

Fig. 1

Study protocol for L5 NRL and SNS. The Sham group (group 1) with the L5 nerve root exposed but not ligated was used as the control. In NRL + SES (group 1), the L5 nerve root was exposed and ligated and the SNS electrode was placed distal to the joint of L4, L5, and L6 nerve roots 2 h after NRL but no electrical stimulation was performed. In the SES groups (Groups 3, 4, and 5), NRL and SNS electrode placement was performed as above described and 2-Hz, 20-Hz, and 60-Hz SNS was performed. Behavioral tests, including the von Frey test and Hargreaves test, were performed 1 day before NRL and on PID 1, 3, 5, and 7

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Journal of Neuroinflammation

ISSN: 1742-2094