Fig. 4

CRS mobilizes peripheral CD4⁺ Th17 cells into the brain in the early phases of stress exposure. a–d Representative flow cytometric analysis and statistical result of CD4⁺ and CD8⁺ T cells contents in the thymus and spleen; e, f representative flow cytometric analysis and statistical result of CD4⁺ Th17 cells contents in the dorsal striatum; g representative confocal images of CD4⁺IL17A⁺ T cells; the expression levels of chemokine h CCL2 in serum; cytokines; i IL-17; and IL-22 in the dorsal striatum. Scale bar, 20 μm. Data are expressed as mean ± SD, Student’s t-test, *p < 0.05, **p < 0.01, ***p < 0.001, compared with control