Systemic inflammatory markers of persistent cerebral edema after aneurysmal subarachnoid hemorrhage

Table 1 Clinical variables in patients according to presence of persistent CE

Variable	Classified by baseline and follow-up SEBES grade
Variable	Persistently poor (n = 21)	Others (n = 114)	p value^†
Age (years)	48.8 ± 11.2	52.9 ± 13.0	0.18
Gender, male	3 (14.3)	28 (24.6)	0.40
Race			0.84
White	15 (71.4)	74 (64.9)
Black	4 (19.0)	27 (23.7)
Asian or others	2 (9.5)	13 (11.4)
Risk factors and comorbidities
Hypertension	12 (57.1)	78 (68.4)	0.31
Dyslipidemia	1 (4.8)	15 (13.2)	0.47
Diabetes mellitus	2 (9.5)	17 (14.9)	0.74
Current smoking	4 (19.0)	46 (40.4)	0.09
Prior coronary artery disease	1 (4.8)	11 (9.6)	0.69
Prior stroke	0 (0.0)	11 (9.6)	0.21
Clinical and radiographic severity of SAH
WFNS grade	4 [3–5]	2 [1–4]	< 0.01
mFS grade	3 [3–3]	3 [3–3]	0.91
IVH	14 (66.7)	75 (65.8)	0.94
Hydrocephalus	17 (81.0)	73 (64.0)	0.13
Therapeutic intervention
Coiling	8 (38.1)	35 (30.7)	0.50

Variables are presented as mean ± SD, median [interquartile range], or number (%)
CE cerebral edema, IVH intraventricular hemorrhage, mFS modified Fisher, SAH subarachnoid hemorrhage, SEBES subarachnoid hemorrhage early brain edema score, WFNS World Federation of Neurological Surgeons
^†p value are calculated by Pearson chi-square test or Fisher’s exact test, or Student’s t test or Mann–Whitney U test as appropriate

ISSN: 1742-2094