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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Human PMSCs-derived small extracellular vesicles alleviate neuropathic pain through miR-26a-5p/Wnt5a in SNI mice model

Fig. 8

miR-26a-5p inhibits spinal microglia activation in SNI mice. A–E Immunofluorescent study revealed IBA1 microglia (green) in the L4–5 spinal dorsal horn of SNI mice. The blue spots are DAPI nuclear staining (Scale bar: 100 μm). F Quantification showing the percentage of IBA1 positive microglia was significantly increased in the SNI and miR-26a-5p/Foxy5 group, compared with sham, SNI/miR-26a-5p, miR-rescue group. Data are represented as mean ± sem. **p < 0.01

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