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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Chronic suppurative otitis media causes macrophage-associated sensorineural hearing loss

Fig. 6

Macrophage morphological changes in the region of spiral ganglion neuron (SGN) in CSOM. Macrophages in cochlear cryosections were labeled with the pan-leukocyte marker CD45 and F4/80. Representative images are shown. Macrophages (arrows) were small with few projections in the control group (A–C, arrows), and they were bigger and round at 3 days (D-F, arrows). Macrophages were larger and irregularly shaped at 7 days (G–I, arrows), and had fine, dendritic projections at 14 days (J–L, arrows). Scale bar = 50 µm. n = 3 per group

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