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Fig. 10 | Journal of Neuroinflammation

Fig. 10

From: Captopril alleviates epilepsy and cognitive impairment by attenuation of C3-mediated inflammation and synaptic phagocytosis

Fig. 10

Intranasal instillation of C3a promotes epileptogenesis after captopril treatment in the KA-induced model of epilepsy. A Representative 2-min EEG recording during epilepsy (7 weeks after KA induction) from the KA, KA + Cap, and KA + Cap + C3a groups are shown. B C3a nasal drip significantly elevates the frequency and total duration of seizures compared to the KA + Cap group 7 weeks after the KA induction. n = 6 rats/group, *p < 0.05, compared to KA; &p < 0.05, compared to KA + Cap, one-way ANOVA followed by Tukey’s post hoc test. Data are presented as mean ± SE

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Journal of Neuroinflammation

ISSN: 1742-2094