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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Investigation and modulation of interleukin-6 following subarachnoid hemorrhage: targeting inflammatory activation for cerebral vasospasm

Fig. 2

IL-6 measurements in both peripheral blood and brain. A peak in IL-6 was seen on post-SAH day 3 and sustained on post-SAH day 5 (p < 0.05) (A). IL-6 was also increased in aneurysmal blood versus sheath blood in human samples (p < 0.05) (B). IL-6 receptor increase was seen in perivascular distribution on post-bleed day 3 (C). IL-6 release was perivascular in distribution (D). Co-localization revealed surrounding reactive astrocytes and IL-6 increased expression with endothelial markers (E). White bar panel B = 60 μm, C = 50 μm, panel D = 30 μm

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Journal of Neuroinflammation

ISSN: 1742-2094