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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Treadmill exercise promotes E3 ubiquitin ligase to remove amyloid β and P-tau and improve cognitive ability in APP/PS1 transgenic mice

Fig. 3

Effect of treadmill exercise on the PI3K/Akt signaling pathway in the hippocampus of wild-type and APP/PS1 transgenic mice (n = 6 for each group). A Western blotting of hippocampal PI3K p110β, PI3K p85α and p-Akt/Ser473. B–D Statistical data showing the effect of exercise on hippocampal PI3K p110β, PI3K p85α and p-Akt/Ser473 in each group of mice. Values are presented as mean ± SEM. Statistically different from WTC, **P < 0.01. Statistically different from ADC, #P < 0.05; ##P < 0.01

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Journal of Neuroinflammation

ISSN: 1742-2094