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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Treadmill exercise promotes E3 ubiquitin ligase to remove amyloid β and P-tau and improve cognitive ability in APP/PS1 transgenic mice

Fig. 4

Effect of treadmill exercise on E3 ubiquitin ligase in the hippocampus of wild-type and APP/PS1 transgenic mice (n = 6 for each group). A, B Statistical data showing the effect of exercise on hippocampal HSFI and HSP70 mRNA in each group of mice. C Western blotting of hippocampal CHIP and HSP70. D, E Statistical data showing the effect of exercise on hippocampal HSP70 and CHIP in each group of mice. Values are presented as mean ± SEM. Statistically different from WTC, *P < 0.05, **P < 0.01. Statistically different from ADC, #P < 0.05; ##P < 0.01

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Journal of Neuroinflammation

ISSN: 1742-2094