Skip to main content
Fig. 11 | Journal of Neuroinflammation

Fig. 11

From: GSK872 and necrostatin-1 protect retinal ganglion cells against necroptosis through inhibition of RIP1/RIP3/MLKL pathway in glutamate-induced retinal excitotoxic model of glaucoma

Fig. 11

Potential molecular mechanisms underlying glutamate-induced RGCs necroptosis and NLRP3 inflammasome activation. GSK872 and Nec-1 prevent RGCs from necroptosis and suppressed NLRP3 inflammasome activation and ROS overproduction by inhibiting the RIP1/RIP3/MLKL pathway in a glutamate-induced excitotoxic glaucoma model

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094