Fig. 6

Attenuation of BPRA injury-induced neuroinflammation in the injured spinal cord in AR^−/− mice. A, B Representative images of Iba1 and GFAP IF staining with NeuN. C, D Summary of changes in ipsilateral spinal IBA1 and GFAP average fluorescence intensity between AR^−/− and WT mice. Data were analyzed by two-way ANOVA and are presented as the mean ± SEM, n = 5 mice/group, ^####p < 0.0001, WT vs. sham group, ^{^^^^}p < 0.0001, AR^−/− vs. sham group, ****p < 0.0001, WT vs. sham group. Scale bar = 50 μm (A, B)