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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Hippocampal microRNA-26a-3p deficit contributes to neuroinflammation and behavioral disorders via p38 MAPK signaling pathway in rats

Fig. 6

The p38 MAPK mediated the miR-26a-3p deficiency-induced behavior disorders. A Experimental paradigm of rats injected AAV-miR-26a-3p sponge virus followed by administration of SB203580, a specific antagonist of p38 MAPK. B Behavioral responses of OFT in miR-26a-3p knock-down and SB203580-treated rats. C Behavioral responses of EPM in miR-26a-3p knock-down and SB203580-treated rats. D Behavioral responses of FST in each group. E Behavioral responses of tail suspension test (TST) in each group. F Behavioral responses of novel object recognition test (NORT) in each group

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