Table 5 Concentration of cytokines/chemokines after α-CD3/α-CD28 stimulation

Growth factors

G-CSF

51.58

(32.84–148.3)

122.9

(32.68–253.6)

59.57

(39.84–169.6)

GM-CSF

3340

(1913–4759)

3576

(2269–6177)

3863

(2176–6296)

IL-7

102.5

(75.29–144.5)

101.2

(71.69–168.7)

92.73

(65.81–134.1)

Innate inflammatory cytokines

TNF-α

4789

(2849–7405)

5777

(3372–9193)

3418

(2538–6753)

TNF-β

513.7

(276.4–797.2)

616.000

(400.9–909)

303

(231.2–651.1)

IL-1α

981.4

(485–1416)

1304

(412–2565)

481.9†

(297.1–753.8)

IL-1β

225.2

(135.6–377.5)

301.7

(138.7–633.7)

150.8

(101.2–242.2)

IL-6

2223

(1286–11,887)

1429

(878.2–2792)

1943

(966.2–4068)

IL-15

2.78

(0.78–3.665)

4.34^#

(1.83–13.45)

3.835

(1.6–9.143)

IFNα2

50.17

(35.4–71.4)

48.33

(32.23–92.72)

45.64

(34.12–71.77)

Innate inflammatory chemokines

Eotaxin

139.5

(104.8–223.7)

178.6

(143–336.2)

149.4

(127.7–233.4)

IL-8

14,590

(11,646–19,854)

18,971

(14,800–20,266)

15,339

(12,828–19,943)

IP-10

1207

(418.2–2672)

843.9

(392.4–1652)

623.2

(199.4–1962)

MCP-1

11,567

(9328–13,727)

12,029

(10,433–13,986)

11,523

(9074–13,589)

MIP-1β

3369

(1613–7961)

3387

(1466–6958)

1792

(1114–5822)

T_H1 cytokines

IFNγ

13,121

(4883–26,333)

13,157

(3595–27,204)

5084†

(2472–11,965)

IL-2

101.3

(31.31–289.6)

96.61

(49.06–224.5)

57.24

(24.56–174.4)

IL-12p40

150.2

(112.2–233.9)

150.2

(84.96–275.9)

141.3

(97.14–192.8)

IL-12p70

73.66

(49.81–118.2)

94.27

(34.4–157.8)

67.83

(45.71–116.1)

T_H2 cytokines

IL-4

102.8

(52.07–150)

83.22

(56.47–204.2)

75.58

(44.41–117.8)

IL-5

84.22

(44.73–174.1)

127.5

(31.31–198.4)

86.28

(34.56–202.5)

IL-13

1651

(1053–2626)

2080

(1109–3263)

1504

(859.3–3230)

T_H17 cytokine

IL-17

127.5

(73.49–239.1)

167.1

(123.5–423.7)

148.6

(53.14–224.7)

Regulatory cytokines

IL-10

781.2

(480.6–1224)

588.3

(296.2–1056)

465.9

(277.5–914.1)

TGF-β

2152

(1190–3307)

2040

(1110–3158)

2301

(1266–2874)