Fig. 3

Hippocampal pro-inflammatory cytokines in silica-instilled mice. Hippocampal IL-1β, IL-6 and TNF-α were determined by ELISA 24 h (A–C; N = 8 Ctrl mice, 10 Si mice) or 15 d (D–F; N = 8 Ctrl mice, 9 Si mice) after intratracheal administration of saline (Ctrl) or silica (Si). Data are expressed as mean ± SEM. *p < 0.05, Student’s t-test