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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: The upregulation of NLRP3 inflammasome in dorsal root ganglion by ten-eleven translocation methylcytosine dioxygenase 2 (TET2) contributed to diabetic neuropathic pain in mice

Fig. 1

Intraperitoneal injection of STZ induced DNP. A Flowchart of the experiment design. B Fasting blood glucose levels were measured in the STZ-treated and control mice. n = 14, ***p < 0.001, two-way ANOVA with Bonferroni post hoc test. C Bodyweight in the STZ-treated and control mice. n = 14, *p < 0.05, ***p < 0.001, two-way ANOVA with Bonferroni post hoc test. D, E The level of HbA1c in STZ-treated and control mice. n = 6, * p < 0.05, one-way ANOVA with Tukey’s post hoc test. F The glucose tolerance test in STZ-treated and control mice. n = 9, *** p < 0.001 STZ 8 w versus control; ###p < 0.001 STZ 2 w versus control, two-way ANOVA with Bonferroni post hoc test. G, H Mechanical allodynia in the left and right paws of the STZ-treated mice. n = 14, *p < 0.05, ***p < 0.001, two-way ANOVA with Bonferroni post hoc test. I, J Thermal hyposensitivity in the left and right paws of the STZ-treated mice. n = 10, **p < 0.01, ***p < 0.001, two-way ANOVA with Bonferroni post hoc test. Experiments were repeated at least 3 times independently

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Journal of Neuroinflammation

ISSN: 1742-2094