Skip to main content
Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Fecal microbiota transplantation and replenishment of short-chain fatty acids protect against chronic cerebral hypoperfusion-induced colonic dysfunction by regulating gut microbiota, differentiation of Th17 cells, and mitochondrial energy metabolism

Fig. 4

FMT and SCFAs treatment alleviate CCH-induced impaired colonic barrier. A Evaluation of body weight. B Representative HE staining in colon (scale bars = 50 µm). C Representative immunofluorescence staining for MUC2 in colon (scale bars = 50 µm). red: MUC2; blue: DAPI. D Relative level of MUC2-positive cells (ratio of sham group, n = 5 per group). The average area of MUC2-positive puncta in sham group is set to 1. E Representative western blot for GPR41, GPR43, HDAC1/2, occludin, claudin1, and GAPDH in colon. F Relative optical density analysis for GPR41, GPR43, HDAC1/2, occludin, claudin1, and GAPDH in colon (n = 4 per group). Data are expressed as mean ± SD. *P < 0.05 vs. sham group. #P < 0.05 vs. BCCAo group

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094