Fig. 10

Lactococcus lactis E001-B-8 attenuated the depressive symptoms mice exposed to CUMS. a Experimental design diagram. b Changes in body weight of mice. c Changes in blood sugar. d Content of 5-HT in hippocampus. e Road map of the open field experiment. f Ratio of distance between center and periphery. g Length of the total journey. h Center to peripheral delay time. i Sugar water preference. j Forced to swim immobile time. k Tail suspension experiment immobility time. Each value represents the mean ± SEM. *p < 0.05, **p < 0.01 and ***p < 0.001 means difference of Control vs. CUMS + Vehicle, CUMS + FLX vs. CUMS + Lactococcus lactis E001-B-8 at the same point