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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Exploring the neuroprotective effects of montelukast on brain inflammation and metabolism in a rat model of quinolinic acid-induced striatal neurotoxicity

Fig. 6

Representative [18F]-FDG PET coronal images of SD rats before (red histogram bars) and 4 months after QA injection (blue histogram bars), treated with VEH or 10 mg/kg of MLK, co-registered to MRI (A). [18F]-FDG uptake was evaluated in the right striatum (B) and cortical regions (CE) and it is expressed as a ratio to the global. Mixed-effects two-way ANOVA with bootstrap: ##p < 0.01, ###p < 0.001, ####p < 0.0001, pre-lesion vs post-lesion; *p < 0.05, **p < 0.01, VEH vs MLK. Data are plotted as mean ± SEM

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