Fig. 4

Genetic deletion of Mac1 impedes P + M-elicited neuroinflammation. A Representative pictures of Iba-1 staining in WT and Mac1^−/− mice. B Quantification of Iba-1 immunostaining. (C, D) The mRNA levels of iNOS (C) and TNFα (D) in WT and Mac1^−/− mice. E Representative blots of iNOS and TNFα in mice and the quantification of the blots. *p < 0.05. **p < 0.01 for comparison between Con & P + M groups; ^#p < 0.05 for comparison between WT-P + M & Mac1^−/−-P + M groups; Scale bar = 50 μm