Fig. 5
From: Metabolic reprogramming and lipid droplets are involved in Zika virus replication in neural cells
Effect of iDGAT-1 treatment on lipid droplet biogenesis and ZIKV replication in human neural stem cells. A Representative images of NSCs 48 h after ZIKV infection at an MOI of 1 treated with 50 µM DGAT-1 inhibitor (A922500) and stained with Oil Red O (red) and DAPI (blue) for nuclei. The scale bar represents 10 µm in range. B Quantification of the fluorescent area per cell in each group. C Effect of the DGAT-1 inhibitor on ZIKV replication at 48 hpi in NSCs. Data information: In B, C, data are presented as the means ± SEMs of three independent experiments. *P < 0.05 mock- versus ZIKV-infected cells. #P < 0.05 ZIKV-infected cells versus A922500 treatments