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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: IFNAR signaling of neuroectodermal cells is essential for the survival of C57BL/6 mice infected with Theiler’s murine encephalomyelitis virus

Fig. 2

IFNAR signaling of neuroectodermal cells critically affects survival of TMEV-infected mice. Kaplan–Meier survival curves show the survival data of TMEV-infected IFNAR−/− (n = 19), NesCre±IFNARfl/fl (n = 9), GFAPCre±IFNARfl/fl (n = 9), Syn1Cre±IFNARfl/fl (n = 10) and Cre−/−IFNARfl/fl mice (n = 10) as well as tamoxifen (Tam)-treated Sall1CreER± mice (n = 5) and Sall1CreER−/− control mice (n = 5). Note the low survival rate of IFNAR−/− and NesCre±IFNARfl/fl mice, intermediate survival rate of GFAPCre±IFNARfl/fl, Syn1Cre±IFNARfl/fl and Sall1CreER± mice and 100% survival of Cre−/−IFNARfl/fl and Sall1CreER−/− control mice

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Journal of Neuroinflammation

ISSN: 1742-2094