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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Exogenous monocyte myeloid-derived suppressor cells ameliorate immune imbalance, neuroinflammation and cognitive impairment in 5xFAD mice infected with Porphyromonas gingivalis

Fig. 1

Pg exacerbated cognitive impairment and neuroinflammation in 5xFAD transgenic mice. A Escape latencies of the two groups of mice in the spatial acquisition trial of the Morris water maze (MWM). B Times of mice crossing over the platform in the probe trial of the MWM. C Time of mice spent in the target quadrant (TQ) in the probe trial of the MWM. D Representative images presenting amyloid plaque and Iba-1-positive cells in the cortex and hippocampus regions. E, F Statistical results of D were shown. Data are presented as means ± SEM. * p < 0.05; ** p < 0.01. Scale bar, 50 μm

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Journal of Neuroinflammation

ISSN: 1742-2094