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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: [18F]F-DED PET imaging of reactive astrogliosis in neurodegenerative diseases: preclinical proof of concept and first-in-human data

Fig. 1

A, B [18F]F-DED cardiac blood input curves and hippocampal time-activity-curves in comparison of PS2APP (green) and wild-type (grey) mice. C Image-derived input function derived [18F]F-DED VT in hippocampus and cerebellum of PS2APP and age matched wild-type mice at 5 and 19 months of age. D Coronal and sagittal slices of [18F]F-DED VT in PS2APP and age-matched wild-type mice are illustrated upon a MRI template. E Immunohistochemistry of similar GFAP and MAO-B levels in the cerebellum of PS2APP and wild-type mice at 19 months of age

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Journal of Neuroinflammation

ISSN: 1742-2094