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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: [18F]F-DED PET imaging of reactive astrogliosis in neurodegenerative diseases: preclinical proof of concept and first-in-human data

Fig. 4

A Life-course kinetics for PS2APP mice as expressed by standardized differences (z-score) in hippocampus for the 3 radiotracers. B Coronal planes of z-scores for the three radiotracers. C Sagittal plane of the hippocampus/subiculum of wild type and PS2APP mice stained against GFAP, Iba1 and Aβ at 5, 13 and 19 months of age. D Mean (± SD) GFAP, Iba1 and Aβ staining (area-%) for PS2APP animals at different ages compared to age-matched wild-type animals

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Journal of Neuroinflammation

ISSN: 1742-2094