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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: N,N-Dimethyl-3β-hydroxycholenamide attenuates neuronal death and retinal inflammation in retinal ischemia/reperfusion injury by inhibiting Ninjurin 1

Fig. 1

Security evaluation of DMHCA systemic administration on body weight and serum lipid levels in mice. a Molecular formula of DMHCA. b Serum lipid level in the Sham, RIR, and RIR + DMHCA treatment groups. Detection of triglycerides (TG), total cholesterol (TC), high-density lipoprotein (HDL) cholesterol and low-density lipoprotein (LDL) cholesterol concentrations. Sham, control C57BL/6J with sham operation; RIR, retinal ischemia/reperfusion injury model mice; RIR + DMHCA, DMHCA treatment with RIR mice; n = 3–6. ns, P > 0.05. c Body weight in sham and RIR group: mean C57BL/6 with normal feed and DMHCA group: 80 mg/kg DMHCA of body weight/day daily via oral gavage for 7 days treatment. n = 6. Data are expressed as means ± standard deviation

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Journal of Neuroinflammation

ISSN: 1742-2094