Fig. 1

ICM ameliorated sepsis-induced cognitive impairment. A Flow chart of the experiment. B Comparison of the mouse survival rates among the four groups. C Comparison of the mouse body weights among the four groups. D–F OFT performance among the four groups. G NOR performance among the four groups. H Y maze test performance among the four groups. Data are presented as the mean ± SEM (n = 8–12 mice per group). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 vs. the indicated groups