Fig. 4

ICM reversed the enhanced phagocytic activity of microglia in the hippocampus of SAE mice. A Representative images of immunofluorescence staining of CD68 (green) and Iba-1 (red) and colocalization in the hippocampus, scale bar = 5 μm; B quantification of the percentage of CD68 area within Iba-1⁺ cells (microglia) in the hippocampus among the four groups. Data are presented as the mean ± SEM (n = 4–6 mice/group). ****P < 0.0001 vs. the indicated groups