Fig. 6

ICM ameliorated abnormal neuronal morphology and loss of dendritic spines in the hippocampus of SAE mice. A Sholl analysis pattern map of neuronal morphology; B quantification of dendritic intersections of neuronal dendrites in the hippocampus among the four groups; C representative images of hippocampal neuronal tracings; D quantification of the number of neuronal branches in the hippocampus among the four groups; E quantification of the total length of neuronal branches in the hippocampus among the four groups; F representative images of the dendritic spines of hippocampal neurons; G quantification of dendritic spine density of neurons in the hippocampus among the four groups, scale bar = 10 μm. Data are presented as the mean ± SEM (n = 4 mice/group). ****P < 0.0001 vs. the indicated groups