Table 1 Characteristics of the population
Depression (N = 106) | Healthy (N = 106) | p-value | |
|---|---|---|---|
Females (%) | 71 (67.0) | 71 (67.0) | 1.000 |
Males (%) | 35 (33.0) | 35 (33.0) | 1.000 |
Age in years (SD) | 26.0 (7.6) | 26.4 (6.8) | 0.701 |
BMI (SD) | 24.0 (5.5) | 23.7 (4.2) | 0.698 |
Weekly use of alcohol in units (SD) | 3.2 (3.9) | 5.0 (6.5) | 0.016 |
Smokers (%) | 32 (30.2) | 13 (12.3) | 0.001 |
Antidepressant medication (%) | 35 (33.0) | 0 (0.0) | < 0.001 |
Antipsychotic medication (%) | 12 (11.3) | 0 (0.0) | < 0.001 |
Time from diagnosis to inclusion, mean weeks (SD) | 4.0 (5.5) | NA | NA |
Outpatients (%) | 89 (84.0) | NA | NA |
Rating scale scoresc | |||
HDRS-17 (SD) | 20.6 (6.3) | 1.1 (1.5) | < 0.001 |
MADRS-10 (SD) | 29.5 (7.6) | 1.2 (1.7) | < 0.001 |
HARS (SD) | 20.7 (9.3) | 2.0 (2.2) | < 0.001 |
PANSS total (SD) | 48.8 (7.2) | 31.5 (2.1) | < 0.001 |
GAF-F (SD) | 49.4 (12.9) | 88.9 (5.1) | < 0.001 |
BACS compositea (SD) | − 0.4 (0.6) | 0.0 (0.6) | < 0.001 |
MMSE total (SD) | 29.1 (1.2) | 29.4 (1.0) | 0.053 |
MoCA (SD) | 27.6 (2.0) | 28.0 (2.0) | 0.143 |
Serum hs-CRP mg/L (SD)b | 0.71 (3.66) | 0.71 (3.74) | 0.980 |
Serum white blood cell count × 109L (SD)b | 5.79 (1.29) | 5.79 (1.27) | 0.977 |