Fig. 6
From: Tregs dysfunction aggravates postoperative cognitive impairment in aged mice
Tregs ablation restores the structure of the blood–brain barrier in aged mice. A Fluorescence signals and quantification of 40 kDa dextran in the mouse hippocampus. DAPI labeled the nuclei (blue), CD31 labeled endothelial cells (green), and dextran stained red (Texas red). Immunofluorescence signals and quantification of claudin1 (B) and claudin5 (C) in the CA3 region of the hippocampus. DAPI labeled the nuclei (blue), CD31 labeled endothelial cells (red), claudin1 or claudin5 stained green. Magnification, ×200, *P < 0.05 n = 6