Fig. 6From: TREM2 deficiency inhibits microglial activation and aggravates demyelinating injury in neuromyelitis optica spectrum disorderGraphic abstract. The absence of TREM2 results in diminished activation of microglia, which obstructs the phagocytic process and degradation of myelin debris by these cells. As a result, the repair of the myelin sheath by oligodendrocytes is impededBack to article page