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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Prominent epigenetic and transcriptomic changes in CD4+ and CD8+ T cells during and after pregnancy in women with multiple sclerosis and controls

Fig. 5

Pregnancy induces similar changes irrespective of disease. Comparison of the differentially methylated CpGs and differentially expressed genes during (3rd-1st) and after (PP-3rd) pregnancy in women with MS and healthy controls (HC) in A CD4+ and B CD8+. The axes indicate the change of methylation and expression during and after pregnancy as measured by the log2 of the limma coefficients ÎČd,3rd - ÎČd,1st and ÎČd,PP - ÎČd,3rd, respectively, where the disease group d (MS or HC) is specified in the axis labels. The percentages of the dots in each area are shown. The colors are based on the density of the dots where darker color represents a higher density. HC healthy controls, MS multiple sclerosis

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Journal of Neuroinflammation

ISSN: 1742-2094