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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: PLPP/CIN-mediated NF2 S10 dephosphorylation distinctly regulates kainate-induced seizure susceptibility and neuronal death through PAK1-NF-κB-COX-2-PTGES2 signaling pathway

Fig. 8

Scheme of the role of PLPP/CIN-mediated NF2 S10 dephosphorylation in response to KA. Following KA treatment, PLPP/CIN-mediated NF2 S10 dephosphorylation may activate PAK1-NF-κB-COX-2-PTGES2 signaling pathway in neurons, which would subsequently increase the latency of seizure on-set and CA3 neuronal damage in response to KA

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Journal of Neuroinflammation

ISSN: 1742-2094