Control | PDD | DLB | AD | p-value | |
---|---|---|---|---|---|
Maximum n | 18 | 22 | 21 | 14 | |
Age at death, y | 82.8 (1.2) | 82.4 (1.0) | 83.1 (1.6) | 85.6 (1.5) | 0.41 |
Female, % | 9 (50.0) | 11 (50.0) | 11 (52.4) | 8 (57.1) | 0.98 |
Post-mortem intervala, h | 41.5 (5.7) | 37.3 (3.6) | 44.6 (6.2) | 39.0 (6.5) | 0.78 |
Tissue pH | 6.4 (0.1) | 6.5 (0.1) | 6.2 (0.1) | 6.4 (0.1) | 0.11 |
MMSE decline per yearb | NA | 2.3 (0.3) | 3.0 (0.5) | 4.0 (1.2) | 0.30 |
Predeath MMSEc | NA | 10.9 (8.2) | 12.2 (5.1) | 8.4 (7.9) | 0.52 |
Duration of dementiad, y | NA | 3.7 (0.6) | 6.4 (0.9)† | 9.7 (0.8)† | < 0.001 |
Duration of parkinsonisme, y | NA | 12.9 (1.3) | 2.9 (0.7) | NA | < 0.001 |
Braak stagef, n | |||||
0–II | 13 | 15 | 4 | 0 | NA |
III–IV | 0 | 6 | 8 | 2 | NA |
V–VI | 0 | 1 | 9 | 11 | NA |
NP scoreg | 0.45 (0.2) | 0.63 (0.1) | 2.10 (0.2)*† | 2.92 (0.1)*† | < 0.001 |
NFT scoreh | 0.09 (0.1) | 0.37 (0.1) | 1.40 (0.2)*† | 2.83 (0.2)*†‡ | < 0.001 |
LB scrorei | 0 | 0.89 (0.2)* | 1.75 (0.3)* | 0.25 (0.1)‡ | < 0.001 |