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Fig. 14 | Journal of Neuroinflammation

Fig. 14

From: Preclinical investigation in FAAH inhibition as a neuroprotective therapy for frontotemporal dementia using TDP-43 transgenic male mice

Fig. 14

Behavioural data obtained in FTD and wildtype male mice at PND90 in the Elevated Plus Maze (panels A–E) and Social Interaction (panels F–H) tests after a chronic treatment with URB597 or vehicle. Details in the text. Data were expressed as means ± SEM and were analysed by one-way or two-way, as required, analysis of variance followed by the Bonferroni test (*p < 0.05, **p < 0.01, ***p < 0.005 versus wildtype mice treated with vehicle; #p < 0.05 versus FTD mice treated with vehicle; @p < 0.05, @@p < 0.01 versus the same genotype and treatment for each type of active contacts)

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