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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Stressor control and regional inflammatory responses in the brain: regulation by the basolateral amygdala

Fig. 1

Changes to BLA input during stressor controllability differentially activates immune-related pathways in a regional manner. Heatmap displaying sample’s directed global significance pathway scores for hippocampus (HPC) and medial prefrontal cortex (mPFC) in A, B escapable (ES) and inescapable (IS) stress groups compared to home cage (HC); C, D ES and IS groups with inhibitory opto (ESOi and ISOi, respectively) compared to home cage with control vector (CHCO), and E, F ES and IS groups with excitatory opto (ESOe and ISOe, respectively) compared to CHCO. Red denotes neuroinflammatory-related pathway gene sets whose genes within exhibit extensive over-expression; green denotes gene sets with extensive under-expression. Mean scores are plotted to show how they vary across treatment conditions

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Journal of Neuroinflammation

ISSN: 1742-2094