Skip to main content
Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Microglia-derived TNF-α contributes to RVLM neuronal mitochondrial dysfunction via blocking the AMPK–Sirt3 pathway in stress-induced hypertension

Fig. 8

Schematic diagram illustrating the mechanisms of the pressor effect of microglia-derived TNF-α via impairing neuronal mitochondrial function in the RVLM. A769662: AMPK activator; CAT: catalase; ETC: electron transport chain; MMP: mitochondrial membrane potential; R7050: TNF-α receptor antagonist; ROS: reactive oxygen species; SOD: superoxide dismutase; TNF-α: tumor necrosis factor-α

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094