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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Varicella-zoster virus proteome-wide T-cell screening demonstrates low prevalence of virus-specific CD8 T-cells in latently infected human trigeminal ganglia

Fig. 1

HSV-1 and VZV responses of human TG-derived T-cell lines. A Gating strategy applied to determine T-cell reactivity, consisting of selection of viable cells followed by size exclusion and selection of single cells, selection of CD3+ T-cells, and finally selection of CD3+CD4+ and CD3+CD8+ T-cells. FSC-A, forward scatter—area; SSC-A, side scatter—area; FSC-H, forward scatter—height. B Flow cytometry analysis of IFNγ production by CD4 T-cells derived from TG donors TG02–TG05 following 6 h of co-culture with autologous B-LCL pulsed with lysates derived from mock, HSV-1, or VZV-infected ARPE-19 cells. C Flow cytometry analysis of IFNγ production by CD8 T-cells following 6 h of coculture with autologous mock- or HSV-1-infected B-LCL. Numbers indicate percentages of cells within the respective gate

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Journal of Neuroinflammation

ISSN: 1742-2094