Varicella-zoster virus proteome-wide T-cell screening demonstrates low prevalence of virus-specific CD8 T-cells in latently infected human trigeminal ganglia

Table 1 Virus-specific T-cell reactivity in TG-derived T-cell lines

*Net percentages of virus reactive T-cells in human TG-derived T-cell lines, as determined by flow cytometric detection of intracellular IFNγ expression following coculture with autologous B-LCL infected with HSV-1 (for CD8) or pulsed with HSV-1 or VZV lysate (for CD4). T-cell reactivities to mock-infected B-LCL were subtracted. NA, not applicable as B-LCL pulsed with exogenous antigens do not efficiently present antigens to CD8 T-cells

ISSN: 1742-2094