Fig. 2
From: Microglial cell response to experimental periodontal disease
Impact of ligature-induced periodontal disease on microglial cell activation in vivo. A Multiparametric analysis of microglia (CD45low CD11b+) by flow cytometry, T-SNE plots indicate CX3CR1, MHCII, and CD68 expression on concatenated data (n = 3 per group). B Differential expression of microglial markers in healthy animals (baseline) and animals with experimental periodontal disease for 1, 10, 20, or 30 days. Red and purple arrows highlight increased expression of CX3CR1 and MHCII, respectively. C Percentage of CD68 + (high) D MHCII + and E CX3CR1 + in microglia. F Mean fluorescence intensity (MFI) of MHCII within MHCII + microglial cells. (Mean ± SEM, ANOVA, *p < 0.05, **p < 0.01)