Fig. 1

PRG treatment attenuated EAU symptoms and alleviated intraocular inflammation. A The representative fundus images of EAU and PRG groups (left). The white arrows indicate inflammatory exudation and linear lesions. The column charts showing the clinical scores between two groups (n = 5/group, right). B The representative H&E-stained images of EAU and PRG groups (left). Scale bars: 50 μm. The black arrows indicate retinal folding. The column charts showing the histological scores between two groups (n = 5/group, right). The flow cytometry histograms (left) and column charts (right) showing the percentage of CD45 + (C) and CD4 + cells (D) in retinal cells of two groups (n = 5/group). The flow cytometry histograms (left) and column charts (right) showing the percentage of CD4 + IL-17A + Th17 (E) and CD4 + IFN-γ + Th1 cells (F) in retinal cells of two groups (n = 5/group). Significance in A–F was calculated using two-tailed unpaired Student's t-test; **P < 0.01, ***P < 0.001, ****P < 0.0001