Fig. 2
From: Progesterone attenuates Th17-cell pathogenicity in autoimmune uveitis via Id2/Pim1 axis
PRG treatment altered the immune cell profile of EAU. A Schematic diagram of experimental design for scRNA-seq analysis of CDLNs cells from Naïve group, EAU group and PRG group. B t-SNE plot showing the immune cell types of CDLNs in scRNA-seq. C Line charts showing the proportion of immune cell types, respectively, among three groups. D Volcano plot showing the EAU-DEGs in all cells. E Volcano plot showing the PRG-DEGs in all cells. F Representative GO biological process and pathways enriched in upregulated EAU-DEGs in all cells. G Representative GO biological process and pathways enriched in downregulated PRG-DEGs in all cells. H Rose diagrams showing the number of up and downregulated EAU-DEGs (up) or PRG-DEGs (down) among all immune cell types. I Representative GO biological process and pathways enriched in downregulated PRG-DEGs in CD4 + T cells