Fig. 4

EPC-EXOs attenuate tissue damage and improve functional recovery post-injury. A H&E staining of Sham, Vehicle, and EPC-EXOs group at SCI 28 days. Scale bar: 200 μm. B Quantification of A, n = 3, **P < 0.01, ***P < 0.001. C Representative footprints of animal walking 28 days post-SCI. Blue: front paw print; red: hind paw print. D, E BMS primary score and the BMS subscale score over time post-SCI in Sham, Vehicle and EPC-EXOs group, n = 5, ^nsP > 0.05, *P < 0.05, **P < 0.01, ***P < 0.001. F Representative images of motor-evoked potential (MEP) in Sham, Vehicle, and EPC-EXOs group at 28 days post-SCI. n = 6. G, H Quantification of F, n = 6, **P < 0.01