Fig. 5

LC–HRMS lipid analysis of DRGs and spinal cord from vehicle and SAFit2-treated paclitaxel mice. A Distribution of measured lipid classes of both tissues in LC–HRMS analysis. B Relative frequencies of lipid classes in lumbar DRGs and spinal cord from SAFit2-treated animals, which were normalized to those of vehicle-treated animals. C Violin plots comparing fatty acid levels of spinal cord samples from vehicle and SAFit2-treated animals. The data represent the mean ± SEM from five mice per group. * p < 0.05 Student’s t-test with Welch’s correction. DRGs dorsal root ganglia, SAFit2 selective antagonist of FKBP51 by induced fit 2, LC–HRMS liquid chromatography–high-resolution mass spectrometry