Fig. 1

Effect of ovariectomy on acute stroke outcomes in RS females. A Kaplan–Meier survival plot. B Representative images of TTC-stained sections obtained 5d post-MCAo. C Histogram depicting mean (± SEM) infarct volume. D Histogram of mean (± SEM) latency to remove the adhesive tape pre-, 2 days post-, and 5 days post-MCAo. E Vibrissae-evoked forelimb placement task for same-side stimulation. F Vibrissae-evoked forelimb placement task for cross-midline stimulation. G Expression of VEGF and (H) GM-CSF in the ischemic hemisphere. N = 14 (intact) and n = 14 (OVX) for A–F. N = 8 (intact) and n = 7 (OVX) for G, H. *p ≤ 0.05