Fig. 5
From: Neuroprotective effects of GSK-343 in an in vivo model of MPTP-induced nigrostriatal degeneration
Effects of GSK-343 on the myelination process. LFB staining showed a significant loss of myelin in MPTP-injected mice (B, B1; score F) compared to Sham mice (A, A1; score F). Treatment with GSK-343 significantly restored the myelin presence (C, C1, D, D1, E, E1; score F). Data are representative of at least three independent experiments. Values are means ± SEM. One-way ANOVA test. ***p < 0.001 vs Sham; ##p < 0.01 vs MPTP; ###p < 0.001 vs MPTP