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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: Disease-modifying effects of a glial-targeted inducible nitric oxide synthase inhibitor (1400W) in mixed-sex cohorts of a rat soman (GD) model of epilepsy

Fig. 9

A Telemetry experimental design, initial SE severity quantification and grouping (C, D). A telemetry device was implanted 2 weeks before exposure to soman. B A representative EEG trace during SE is shown. C Animals were grouped based on the initial behavioral SE severity. There were no significant differences in SE severity between the vehicle and 1400W treated groups in either mixed-sex cohort or males or females (C, D). C Unpaired t-test, n = 19–20 for mixed-sex cohort (n = 8–12/sex); (D mixed-sex) Mann–Whitney test, n = 12–16; (D males–females) unpaired t-test, n = 5–8. NS, non-significant

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