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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Transcriptome alterations in peripheral blood B cells of patients with multiple sclerosis receiving immune reconstitution therapy

Fig. 5

Protein–protein interaction network of differentially expressed genes. The gene symbols of the top 500 differentially expressed genes (DEGs) were entered in the GeneMANIA Cytoscape plugin [57, 58]. The search identified 428 physical interactions (blue edges) between 173 gene products (nodes colored by cluster membership). The other top DEGs were not linked by protein–protein interactions and are thus not shown in the network. The size of the nodes corresponds to the number of edges

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