Table 3 Correlations of pathological and microglial markers across the temporal (TL) and cerebellar (Cb) cortex (all Braak stages)

Aβ (TL)

r_s = 0.287

P = 0.032

r_s = 0.268

P = 0.04

r_s = 0.176

P = 0.193

r_s = 0.019

P = 0.889

r_s = 0.295

P = 0.027

r_s = 0.042

P = 0.765

r_s = − 0.118

P = 0.392

r_s = 0.061

P = 0.646

r_s = − 0.033

P = 0.812

Aβ (Cb)

r_s = 0.177

P = 0.187

r_s = 0.296

P = 0.026

r_s = 0.272

P = 0.04

r_s = 0.133

P = 0.33

r_s = 0.219

P = 0.102

r_s = 0.065

P = 0.647

r_s = − 0.143

P = 0.294

r_s = 0.121

P = 0.37

r_s = − 0.013

P = 0.927

pTau (TL)

r_s = 0.339

P = 0.012

r_s = 0.465

P < 0.001

r_s = 0.095

P = 0.494

r_s = 0.100

P = 0.463

r_s = 0.319

P = 0.019

r_s = 0.129

P = 0.368

r_s = − 0.23

P = 0.098

r_s = 0.099

P = 0.465

r_s = − 0.184

P = 0.191

pTau (Cb)

r_s = 0.081

P = 0.547

r_s = 0.141

P = 0.297

r_s = 0.079

P = 0.561

r_s = − 0.004

P = 0.979

r_s = − 0.036

P = 0.802

r_s = − 0.084

P = 0.539

r_s = 0.104

P = 0.442

r_s = 0.214

P = 0.12

TSPO (TL)

r_s = 0.220

0 = 0.101

r_s = 0.010

P = 941

r_s = 0.284

P = 0.033

r_s = 0.139

P = 0.316

r_s = 0.083

P = 0.544

r_s = 0.356

P = 0.005

r_s = − 0.071

P = 0.612

TSPO (Cb)

r_s = − 0.091

P = 0.507

r_s = 0.230

P = 0.085

r_s = 0.274

P = 0.05

r_s = 0.164

P = 0.228

r_s = 0.204

P = 0.129

r_s = 0.015

P = 0.913

Iba1 (TL)

r_s = 0.256

P = 0.057

r_s = 0.082

P = 0.56

r_s = − 0.008

P = 0.955

r_s = − 0.103

P = 0.436

r_s = − 0.279

P = 0.043

Iba1 (Cb)

r_s = 0.119

P = 0.402

r_s = − 0.011

P = 0.933

r_s = 0.077

P = 0.569

r_s = − 0.071

P = 0.61

HLA–DR (TL)

r_s = 0.548

P < 0.001

r_s = 0.244

P = 0.075

r_s = − 0.08

P = 0.583

HLA–DR (Cb)

r_s = 0.088

P = 0.518

r_s = 0.087

P = 0.536

MSR-A (TL)

r_s = 0.043

P = 0.759